Lortab is a combination of Acetaminophen and hydrocodone. Pain ranging from moderate to severe can be treated with this combination of medications. Acetaminophen and hydrocodone, both known by their generic name Lortab, are medications in the narcotic analgesic combination class. While hydrocodone is an opioid painkiller, paracetamol is a non-opioid. Hydrocodone alters the way your body senses and reacts to pain in the brain. Fever can also be treated with paracetamol. These two components help to reduce discomfort. First, there is the narcotic painkiller hydrocodone; second, there is paracetamol, a potent analgesic that amplifies the effects of hydrocodone.

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