Tramadol differs from other opioids like Oxycodone and Hydrocodone in several important ways, including its mechanism of action, potency, and risk profile.

Key Differences Between Tramadol, Oxycodone, and Hydrocodone:
Mechanism of Action:

Tramadol is a dual-action medication. It works by:
Binding to opioid receptors in the brain, similar to other opioids, to relieve pain.
Inhibiting the reuptake of serotonin and norepinephrine, neurotransmitters involved in mood and pain modulation. This gives Tramadol an additional antidepressant-like effect.
Oxycodone and Hydrocodone: These are more traditional opioids that primarily relieve pain by binding to opioid receptors without the additional serotonin/norepinephrine effect seen in Tramadol.

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