Esophageal cancer is the sixth most common cause of cancer-related deaths worldwide and fourth in developing countries. The esophagus, also known as food pipe, is a muscular hollow tube-like organ that provides passage to swallowed food up to the stomach. Based on the type of cells affected, esophagus cancer can be divided into two major histology types, squamous cells carcinoma (affecting flat cells that line the inner side of the esophagus) and adenocarcinoma (affecting glandular cells that produce mucus and other fluids).

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